Placebos

Via stategic partnerships and appropriate QP (IMP) release, Mawdsleys can provide you with high quality placebo supplies, and overencapsulation services; we can also source all the comparators you need directly from around the globe. So whether you need one hundred placebos or one million comparators for your clinical trial, the search ends with Mawdsleys.

What are Placebos and Comparators?

In controlled clinical trials there is an active treatment group of patients, who receive the active drug, and there is also a control group of patients, who receive an inactive substance called a placebo, which may be sugar pills, liquid placebos, inert fill placebos, or any other custom made placebos. In comparator trials the active drug is compared with similar products which are already available on the market place. For the purpose of the trial these are called comparators , but they may be prescription drugs or well known brands. In blinded trials the patients must not be able to tell which treatment they are receiving, so the placebo and the active drug and any comparators must all look the same. This can be achieved by overencapsulating with the same colour capsule and filling any space inside to make sure the capsule weighs the same. Randomisation is often required to ensure doctors and patients are not aware of who is receiving the active drug and who is receiving the placebo.

What is Randomization?

Randomization is the use of probability (random number generation) to allocate a patient to a particular treatment or control group. Mawdsleys can take care of this for your clinical trial, alongside the blinding process.

What is Blinding?

Blinding means that the treatment a patient receives in a clinical trial is hidden from the patient themselves.

Single Blinding means that the patient does not know which treatment they are receiving but the medical team treating the patient are aware.

Double Blinding means that neither the patient nor the medical team know what treatment the patient is receiving.

Mawdsleys can take care of these complicated procedures on your behalf. A 24 hour code break telephone line or code break envelope will be provided in case of emergency to inform the doctors of the treatment the patient is receiving.

Mawdsleys can also provide the following clinical trial services:

  • Sourcing of clinical trial supplies
  • Distribution of clinical trials
  • Importation into Europe
  • QP IMP Release
  • Blinding
  • Filling, Packaging and labelling
  • Randomisation
  • Manufacturing including overencapsulation
  • Clinical Trial Storage

You might also be interested in:

Clinical Trial Services
Regulatory Services
QP Release Services
Comparator Sourcing
Third Party Logistics


contact Email contact: info@mawdsleys.co.uk